Our progress:

Periplasmic binding protein based biosensors


Vectors for PBP-YFP-CFP chimeras have been constructed
(Wishart group)







PBP-YFP-CFP chimeras have been sucesfully expressed in E.coil
(Wishart group)







PBP-YFP-CFP chimeras have been purified and tested
(Wishart group)







Multiple colours of fluorescent protein for use in biosensors have been engineered
(Campbell group)






Ca2+ biosensor molecule has been sucessfully tested
(Campbell group)






FRET-based biosensor for histone methylation has been constructed and optimized
(Campbell group)